Award review: Studies on taste: molecular biology and food science

• ABE Keiko

  Department of Applied Biological Chemistry, Graduate School of Agriculture and Life Sciences, The University of Tokyo

書誌事項

タイトル別名

• Studies on Taste: Molecular Biology and Food Science

抄録

Taste is indispensable for vertebrate to find a proper way of living by selection of foods at their discretion. It is also a mainstay in the construction of human culture and the food industry, but no systematic information is available regarding the molecular logic of taste signaling and associated chemical entities. Against this backdrop, our research had bumble beginnings in the 1990s and then traced a unique path of development revealing major signaling pathways involving G protein-coupled receptors, Gαi2, PLC-β2, IP₃R3, PLA2IIa, TRPM5, KCNQ1, etc. The validity of our studies on the molecular biology of taste was verified by material science in the case of an enigmatic protein, neoculin, which converts sourness to sweetness. The study should provide new information for better understanding of taste-taste interactions which are important in food design.

収録刊行物

• Ｂｉｏｓｃｉｅｎｃｅ，　Ｂｉｏｔｅｃｈｎｏｌｏｇｙ，　ａｎｄ　Ｂｉｏｃｈｅｍｉｓｔｒｙ

  Ｂｉｏｓｃｉｅｎｃｅ，　Ｂｉｏｔｅｃｈｎｏｌｏｇｙ，　ａｎｄ　Ｂｉｏｃｈｅｍｉｓｔｒｙ 72 (7), 1647-1656, 2008

  公益社団法人 日本農芸化学会

キーワード

• taste reception
• taste signaling
• taste preference-aversion
• neoculin
• human sweet taste receptor

詳細情報

• CRID: 1390282681457310848
• NII論文ID: 10027529260
• NII書誌ID: AA10824164
• DOI: 10.1271/bbb.70690
• ISSN: 13476947
• ISSN: 09168451
• NDL書誌ID: 9595572
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I9595572
• Web Site: http://www.tandfonline.com/doi/pdf/10.1271/bbb.70690
• Web Site: https://search.jamas.or.jp/link/ui/2009046066
• 本文言語コード: en
• データソース種別:
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• 抄録ライセンスフラグ: 使用不可