Reduction of blood pressure by soybean saponins, rennin inhibitors from soybean, in spontaneously hypertensive rats

• HIWATASHI Kazuyuki

  Laboratory of Nutrition, Graduate School of Agricultural Science, Tohoku University Akita Research Institute of Food and Brewing

• SHIRAKAWA Hitoshi

  Laboratory of Nutrition, Graduate School of Agricultural Science, Tohoku University

• HORI Kazuyuki

  Akita Research Institute of Food and Brewing

• YOSHIKI Yumiko

  Department of Food Science, Ishikawa Prefectural University

• SUZUKI Nao

  Akita Research Institute of Food and Brewing

• HOKARI Mika

  Akita Research Institute of Food and Brewing

• KOMAI Michio

  Laboratory of Nutrition, Graduate School of Agricultural Science, Tohoku University

• TAKAHASHI Saori

  Akita Research Institute of Food and Brewing

書誌事項

タイトル別名

• Reduction of Blood Pressure by Soybean Saponins, Renin Inhibitors from Soybean, in Spontaneously Hypertensive Rats

抄録

The effect of commercial purified soybean saponin on renin activity and blood pressure was investigated. Soybean saponin significantly inhibited human renin in vitro with IC₅₀=59.9 μg/ml. Orally administered soybean saponin at 80 mg/kg of body weight per day to spontaneously hypertensive rats for 8 weeks significantly decreased the blood pressure.

収録刊行物

• Ｂｉｏｓｃｉｅｎｃｅ，　Ｂｉｏｔｅｃｈｎｏｌｏｇｙ，　ａｎｄ　Ｂｉｏｃｈｅｍｉｓｔｒｙ

  Ｂｉｏｓｃｉｅｎｃｅ，　Ｂｉｏｔｅｃｈｎｏｌｏｇｙ，　ａｎｄ　Ｂｉｏｃｈｅｍｉｓｔｒｙ 74 (11), 2310-2312, 2010

  公益社団法人 日本農芸化学会

キーワード

• soyasaponin
• soybean
• renin inhibitor
• blood pressure
• spontaneously hypertensive rat

詳細情報

• CRID: 1390282681456103168
• NII論文ID: 10027561804
• NII書誌ID: AA10824164
• DOI: 10.1271/bbb.100328
• ISSN: 13476947
• ISSN: 09168451
• NDL書誌ID: 10899955
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I10899955
• Web Site: http://www.tandfonline.com/doi/pdf/10.1271/bbb.100328
• Web Site: https://search.jamas.or.jp/link/ui/2011238741
• 本文言語コード: en
• データソース種別:
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  • NDL
  • Crossref
  • CiNii Articles
  • KAKEN
• 抄録ライセンスフラグ: 使用不可