Efficacy of methotrexate in the treatment of a HLA-B27-positive Japanease patient with reactive arthritis

• NANKE Yuki

  Institute of Rheumatology, Tokyo Women's Medical University

• YAGO Toru

  Institute of Rheumatology, Tokyo Women's Medical University

• KOBASHIGAWA Tsuyoshi

  Institute of Rheumatology, Tokyo Women's Medical University

• KOTAKE Shigeru

  Institute of Rheumatology, Tokyo Women's Medical University

抄録

  We report a case of reactive arthritis in a 21-year-old man who was successfully treated with methotrexate. In July 2008, the patient experienced arthritis in the left knee 3 days after being diagnosed as having urethritis by the urology clinic. The patient was treated with loxoprofen sodium and fosfomycin calcium at an orthopedic clinic. Antibiotics induced clinical improvement of urethritis, although arthritis became worse. Even after sulphasalazine and corticosteroid were started, polyarthritis remained persistent. Finally, methtrexate was added ; thereafter, polyarthritis and elevated CRP were resolved. HLA-B270502 was positive. Methotrexate could be one of the choices for sulphasalazine-resistant reactive arthritis.<br>

収録刊行物

• 日本臨床免疫学会会誌

  日本臨床免疫学会会誌 33 (5), 283-285, 2010

  日本臨床免疫学会

キーワード

• reactive arthritis
• seronegative
• Chlamydia
• chlamydial
• spondyloarthropathy
• methotrexate

詳細情報

• CRID: 1390001204650746752
• NII論文ID: 10027754104
• NII書誌ID: AN00357971
• DOI: 10.2177/jsci.33.283
• ISSN: 13497413
• ISSN: 09114300
• Web Site: http://www.jstage.jst.go.jp/article/jsci/33/5/33_5_283/_pdf
• Web Site: https://search.jamas.or.jp/link/ui/2011149145
• 本文言語コード: en
• データソース種別:
  • JaLC
  • Crossref
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可