好酸球性中耳炎全国疫学調査

DOI 被引用文献10件 参考文献11件

書誌事項

タイトル別名
  • Epidemiologic Surveillance of "Eosinophilic Otitis Media" in Japan

この論文をさがす

抄録

Despite an increasing number of reports of so called 'eosinophilic otitis media', its nature and pathogenesis are not fully understood. This surveillance was performed in an attempt to investigate the clinical and epidemiologic characteristics of eosinophilic otitis media.<BR>Definite diagnosis was made according to the following four criteria:(a) adult patients with bronchial asthma, (b) extremely viscous middle ear effusion, (c) resistant to usual treatments such as antibiotics, myringotomy, tympanostomy tube insertion, tympanoplasty, etc., and (d) marked eosinophil infiltration in middle ear effusion and/or middle ear mucosa/granulation. Patients who met the first three criteria were judged as suggestive cases.<BR>We sent the primary questionnaires to 1409 hospitals and medical universities all over Japan in which full-time ENT doctors work, and received answers from 628 hospitals. Three hundred and forty-one definite and 446 suggestive cases were presented. The secondary questionnaires were sent to 137 hospitals to survey the details of the presented definite cases.<BR>The disease was predominant in females in their fifties and sixties. Both ears were affected in 81%, and sinusitis was associated in 74% of the patients. Forty-seven percent of the patients had sensorineural hearing loss, and 6% were deaf. The ratio of sensorineural hearing loss was not dependent on the history of sinus surgery (49% vs. 46%, p>0.1). Topical and systemic steroids were used in 78% and 66% of the patients, respectively. The ratio of sensorineural hearing loss was significantly higher in patients who were given systemic steroids than those without systemic steroids (52% vs.34%, p<0.05). Only13% of the patients underwent tympanoplasty, and showed significantly higher ratio of deafness compared to those without tympanoplasty (17%vs.4%, p<0.05). Sensorineural hearing loss was exacerbated postoperatively in most of the deaf patients who underwent tympanoplasty.<BR>These results demonstrated intractable features and poor prognosis of hearing of eosinophilic otitis media.

収録刊行物

被引用文献 (10)*注記

もっと見る

参考文献 (11)*注記

もっと見る

キーワード

詳細情報 詳細情報について

問題の指摘

ページトップへ