Possible Neuro-Sweet Disease Mimicking Brain Tumor in the Medulla Oblongata -Case Report-

• AKIBA Chihiro

  Department of Neurosurgery, Juntendo University Shizuoka Hospital

• ESAKI Takanori

  Department of Neurosurgery, Juntendo University Shizuoka Hospital

• ANDO Maya

  Department of Neurology, Juntendo University Shizuoka Hospital

• FURUYA Tsuyoshi

  Department of Neurology, Juntendo University Shizuoka Hospital

• NODA Kazuyuki

  Department of Neurology, Juntendo University Shizuoka Hospital

• NAKAO Yasuaki

  Department of Neurosurgery, Juntendo University Shizuoka Hospital

• YAMAMOTO Takuji

  Department of Neurosurgery, Juntendo University Shizuoka Hospital

• OKUMA Yasuyuki

  Department of Neurology, Juntendo University Shizuoka Hospital

• MORI Kentaro

  Department of Neurosurgery, Juntendo University Shizuoka Hospital

書誌事項

タイトル別名

• —Case Report—

抄録

A 62-year-old male presented with a rare case of possible neuro-Sweet Disease (NSD) mimicking brain tumor in the medulla oblongata, manifesting as numbness in the bilateral upper and lower extremities, gait disturbance, dysarthria, and swallowing disturbance which gradually deteriorated over 3 months. Magnetic resonance imaging showed a mass lesion in the medulla oblongata, extending to the upper cervical cord with rim enhancement by gadolinium. The preoperative diagnosis was brain tumor, such as glioma, or inflammatory disease. His neurological symptoms gradually deteriorated, so biopsy was performed through the midline suboccipital approach. Histological examination showed infiltration of inflammatory cells, mainly lymphocytes and macrophages. Human leukocyte antigen typing showed Cw1 and B54 which strongly suggested possible NSD. Steroid pulse therapy was started after surgery and the clinical symptoms improved. Neurosurgeons should be aware of inflammatory disorders such as NSD mimicking brain tumor.<br>

収録刊行物

• Neurologia medico-chirurgica

  Neurologia medico-chirurgica 51 (2), 140-143, 2011

  一般社団法人 日本脳神経外科学会

キーワード

• neuro-Sweet disease
• inflammatory disease
• medulla oblongata
• corticosteroid
• brain biopsy

詳細情報

• CRID: 1390001205057709056
• NII論文ID: 10028105016
• NII書誌ID: AN00358613
• DOI: 10.2176/nmc.51.140
• ISSN: 13498029
• ISSN: 04708105
• Web Site: http://www.jstage.jst.go.jp/article/nmc/51/2/51_2_140/_pdf
• Web Site: https://search.jamas.or.jp/link/ui/2011323333
• 本文言語コード: en
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