Inter- and Intra-Observer Variability for Assessment of the Synergy Between Percutaneous Coronary Intervention With TAXUS and Cardiac Surgery (SYNTAX) Score and Association of the SYNTAX Score With Clinical Outcome in Patients Undergoing Unprotected Left Main Stenting in the Real World

• Shiomi Hiroki

  Department of Cardiovascular Medicine, Graduate School of Medicine, Kyoto University

• Tamura Toshihiro

  Division of Cardiology, Tenri Hospital

• Niki Shunichiro

  Department of Cardiovascular Medicine, Graduate School of Medicine, Kyoto University

• Tada Tomohisa

  Department of Cardiovascular Medicine, Graduate School of Medicine, Kyoto University

• Tazaki Junichi

  Department of Cardiovascular Medicine, Graduate School of Medicine, Kyoto University

• Toma Masanao

  Division of Cardiology, Hyogo Prefectural Amagasaki Hospital

• Ono Koh

  Department of Cardiovascular Medicine, Graduate School of Medicine, Kyoto University

• Shioi Tetsuo

  Department of Cardiovascular Medicine, Graduate School of Medicine, Kyoto University

• Morimoto Takeshi

  Center for Medical Education and Clinical Epidemiology Unit, Graduate School of Medicine, Kyoto University

• Akao Masaharu

  Division of Cardiology, Kyoto Medical Center, National Hospital Organization

• Furukawa Yutaka

  Division of Cardiology, Kobe City Medical Center General Hospital

• Nakagawa Yoshihisa

  Division of Cardiology, Tenri Hospital

• Kimura Takeshi

  Department of Cardiovascular Medicine, Graduate School of Medicine, Kyoto University

抄録

Background: The Synergy Between Percutaneous Coronary Intervention With TAXUS and Cardiac Surgery (SYNTAX) score was proposed as a method to evaluate the complexity of coronary anatomy. However, the reproducibility of assessment for the SYNTAX score in unprotected left main coronary artery (ULMCA) disease has not yet been adequately evaluated. The purpose of this study is to assess inter- and intra-observer variability for the assessment of the SYNTAX score in patients undergoing ULMCA stenting in daily clinical practice. Methods and Results: The SYNTAX score of 101 consecutive patients who underwent ULMCA stenting with sirolimus-eluting stent was independently assessed by 2 experienced interventional cardiologists. One of the 2 cardiologists evaluated all the cases again 6 months after the initial assessment. The κ value for inter-observer variability in estimating the SYNTAX score was 0.62 according to the dichotomized analysis (≥33, <33) and 0.58 according to the tertile analysis (<23, 23≤-<33, ≥33), while the intra-observer variability was 0.78 and 0.69, respectively. Patients with a high SYNTAX score (≥33, n=55) compared with those with low or intermediate score (<33, n=46) had a significantly higher rate of target-lesion revascularization (TLR) of the ULMCA lesion at 2 years (24% vs. 4.4%, P=0.01). Conclusions: Both inter- and intra-observer variability for estimating the SYNTAX score were within an acceptable range and a high SYNTAX score showed a higher rate of TLR in patients undergoing ULMCA stenting in daily clinical practice. (Circ J 2011; 75: 1130-1137)<br>

収録刊行物

• Circulation Journal

  Circulation Journal 75 (5), 1130-1137, 2011

  一般社団法人 日本循環器学会

キーワード

• Coronary disease
• Percutaneous coronary intervention
• Revascularization
• SYNTAX score

詳細情報

• CRID: 1390001205104405632
• NII論文ID: 10028147497
• NII書誌ID: AA11591968
• DOI: 10.1253/circj.cj-10-1112
• COI: 1:STN:280:DC%2BC3MvlvVWqsg%3D%3D
• ISSN: 13474820
• ISSN: 13469843
• PubMed: 21467658
• Web Site: http://www.jstage.jst.go.jp/article/circj/75/5/75_CJ-10-1112/_pdf
• Web Site: https://search.jamas.or.jp/link/ui/2011257825
• 本文言語コード: en
• データソース種別:
  • JaLC
  • Crossref
  • PubMed
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可