Endocardial and Epicardial Deformations in Cardiac Amyloidosis and Hypertrophic Cardiomyopathy

• Di Bella Gianluca

  Clinical and Experimental Department of Medicine and Pharmacology, University of Messina

• Minutoli Fabio

  Department of Radiological Sciences, University of Messina

• Pingitore Alessandro

  Clinical Physiology Institute, CNR, Fondazione G. Monasterio, CNR Regione Toscana

• Zito Concetta

  Clinical and Experimental Department of Medicine and Pharmacology, University of Messina

• Mazzeo Anna

  Department of Neurosciences, Psychiatry and Anaesthesiology, University of Messina

• Aquaro Giovanni D.

  Clinical Physiology Institute, CNR, Fondazione G. Monasterio, CNR Regione Toscana

• Di Leo Rita

  Department of Neurosciences, Psychiatry and Anaesthesiology, University of Messina

• Recupero Antonino

  Clinical and Experimental Department of Medicine and Pharmacology, University of Messina

• Stancanelli Claudia

  Department of Neurosciences, Psychiatry and Anaesthesiology, University of Messina

• Baldari Sergio

  Department of Radiological Sciences, University of Messina

• Vita Giuseppe

  Department of Neurosciences, Psychiatry and Anaesthesiology, University of Messina

• Carerj Scipione

  Clinical and Experimental Department of Medicine and Pharmacology, University of Messina

書誌事項

タイトル別名

• – 2-D Feature Strain Echocardiography –

抄録

Background: The aim of the present study was to analyze epicardial (EPI) and endocardial (ENDO) strain (S) in patients with transthyretin-related cardiac amyloidosis (TTR-CA) and hypertrophic cardiomyopathy (HCM) using echocardiography (TTE) with 2-dimensional feature tracking imaging (FTI). Methods and Results: Thirty-three subjects (11 with HCM, 11 with TTR-CA, and 11 healthy subjects as controls) with a New York Heart Association functional class ≤II underwent conventional TTE and FTI. TTE was used for the evaluation of left ventricle (LV) wall thickness, mass, systolic and diastolic function. FTI was used for the evaluation of EPI and ENDO longitudinal, and circumferential, and radial S. LV wall thickness and mass were higher in both TTR-CA and HCM in comparison with controls (P<0.001), but ejection fraction (EF) was similar among patients with TTR-CA, HCM and controls (63±6%, 64±6%, 61±5%, respectively). ENDO and EPI longitudinal and circumferential S and radial S were significantly lower in HCM and TTR-CA when compared with controls (P<0.01). No differences in EPI and ENDO longitudinal S, ENDO circumferential S and radial S were found between TTR-CA and HCM groups, while EPI circumferential S was significantly lower in the TTRCA group (6±3.3%) than in the HCM group (8.1±4.3%; P<0.0001). Conclusions: Longitudinal, circumferential and radial LV deformations are impaired in patients with TTR-CA and HCM with a preserved EF. Impairment of EPI circumferential strain is greater in TTR-CA than in HCM. (Circ J 2011; 75: 1200-1208)<br>

収録刊行物

• Circulation Journal

  Circulation Journal 75 (5), 1200-1208, 2011

  一般社団法人 日本循環器学会

キーワード

• Cardiac amyloidosis
• 2-D Feature strain echocardiography
• Hypertrophic cardiomyopathy
• Myocardial strain

詳細情報

• CRID: 1390001205104382976
• NII論文ID: 10028147758
• NII書誌ID: AA11591968
• DOI: 10.1253/circj.cj-10-0844
• ISSN: 13474820
• ISSN: 13469843
• Web Site: https://www.jstage.jst.go.jp/article/circj/75/5/75_CJ-10-0844/_pdf
• Web Site: https://search.jamas.or.jp/link/ui/2011257834
• 本文言語コード: en
• データソース種別:
  • JaLC
  • Crossref
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可