Selective, high conversion of D-glucose to 5-keto-D-gluconate by Gluconobacter suboxydans

  • ANO Yoshitaka
    Department of Biological Chemistry, Faculty of Agriculture, Yamaguchi University
  • SHINAGAWA Emiko
    Department of Chemical and Biological Engineering, Ube National College of Technology
  • ADACHI Osao
    Department of Biological Chemistry, Faculty of Agriculture, Yamaguchi University
  • TOYAMA Hirohide
    Department of Biological Chemistry, Faculty of Agriculture, Yamaguchi University
  • YAKUSHI Toshiharu
    Department of Biological Chemistry, Faculty of Agriculture, Yamaguchi University
  • MATSUSHITA Kazunobu
    Department of Biological Chemistry, Faculty of Agriculture, Yamaguchi University

書誌事項

タイトル別名
  • Selective, High Conversion of D-Glucose to 5-Keto-D-gluoconate by Gluconobacter suboxydans
  • Selective, High Conversion of <scp>D</scp>-Glucose to 5-Keto-<scp>D</scp>-gluoconate by <i>Gluconobacter suboxydans</i>

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抄録

Selective, high-yield production of 5-keto-D-gluconate (5KGA) from D-glucose by Gluconobacter was achieved without genetic modification. 5KGA production by Gluconobacter suffers byproduct formation of 2-keto-D-gluconate (2KGA). By controlling the medium pH strictly in a range of pH 3.5–4.0, 5KGA was accumulated with 87% conversion yield from D-glucose. The pH dependency of 5KGA formation appeared to be related to that of gluconate oxidizing activity.

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