Thermal Preconditioning Attenuates Exercise-induced Muscle Injury in Mice
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- Nonaka Koji
- Department of Physical Therapy, Faculty of Comprehensive Rehabilitation, Osaka Prefecture University Health Welfare Laboratory, Kibi International University
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- Akiyama Junichi
- Health Welfare Laboratory, Kibi International University
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- Tatsuta Naomi
- Health Welfare Laboratory, Kibi International University
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- Iwata Akira
- Department of Physical Therapy, Faculty of Comprehensive Rehabilitation, Osaka Prefecture University
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[Purpose] The purpose of this study was to demonstrate the preventative effect of thermal preconditioning on exercise-induced muscle injury. [Subjects and Methods] Eight-week old male ICR mice were divided into a control group (Cont) and heat stress group (Heat). Mice in the Heat group were immersed in water at 41.5 ± 0.5°C for 20 minutes, 24 h before exercise. Mice performed downhill running at 22 m/min on a —14 degree incline, for 150 minutes. Before and 24, 48, and 72 h after exercise, the quadriceps femoris muscles were removed to analyze heat shock protein 25 (HSP25) levels before exercise and glucose-6-phosphate dehydrogenase (G6PD) activity at all time points. [Result] HSP25 level before exercise was significantly greater in the Heat group than in the Cont group. G6PD activity was significantly increased at 24, 48, and 72 h in the Cont group, and at 48 h in the Heat group compared with before exercise. Increases in G6PD activity in the Heat group were significantly lower than in the Cont group at 24, 48, and 72 h. [Conclusion] These results suggest that thermal preconditioning induces an increase in HSP25 protein and attenuates exercise-induced muscle injury.<br>
収録刊行物
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- J Phys Ther Sci
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J Phys Ther Sci 23 (3), 409-411, 2011
理学療法科学学会
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詳細情報 詳細情報について
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- CRID
- 1390001204327865600
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- NII論文ID
- 10029034919
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- NII書誌ID
- AA10798949
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- ISSN
- 21875626
- 09155287
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- Crossref
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可