A CASE OF IGG4 RELATED DISEASE SHOWING MORPHOLOGICAL AND HISTOLOGICAL CHANGE OF MAJOR DUODENAL PAPILLA AFTER STEROID THERAPY

• DOUHARA Akitoshi

  Center for Digestive and Liver Diseases, Nara City Hospital.

• SUMIDA Yoshio

  Center for Digestive and Liver Diseases, Nara City Hospital.

• HARA Tasuku

  Center for Digestive and Liver Diseases, Nara City Hospital.

• INADA Yutaka

  Center for Digestive and Liver Diseases, Nara City Hospital.

• YOSHIDA Naohisa

  Department of Gastroenterology and Hepatology, Kyoto Prefectural University of Medicine.

• SAKAI Kyoko

  Center for Digestive and Liver Diseases, Nara City Hospital.

• KANEMASA Kazuyuki

  Center for Digestive and Liver Diseases, Nara City Hospital.

• IMAI Shunsuke

  Department of Pathology, Nara City Hospital.

Bibliographic Information

Other Title

• ステロイド治療前後で十二指腸主乳頭の変化を観察し得たIgG4関連疾患の1例

Abstract

A 77-year-old man with jaundice was referred to our hospital. We found elevated level of serum hepatobiliary enzymes, IgG, and IgG4. Imaging studies demonstrated a pancreas head mass, segmental narrowing of the main pancreatic duct with an irregular wall in the pancreas head, and strictures of the intrahepatic and extrahepatic bile duct. His major duodenal papilla was swollen on duodenoscopy during endoscopic retrograde cholangiopancreatography, and infiltration of abundant IgG4-positive plasma cells was detected in the biopsy specimens taken from the swollen papilla. We diagnosed IgG4-related sclerosing cholangitis with autoimmune pancreatitis. After steroid therapy, his jaundice and the swelling of the pancreatic head were relieved and the swollen papilla with the abundant infiltration of IgG4-positive plasma cells disappeared.

Journal

• GASTROENTEROLOGICAL ENDOSCOPY

  GASTROENTEROLOGICAL ENDOSCOPY 53 (6), 1617-1625, 2011

  Japan Gastroenterological Endoscopy Society

Keywords

• IgG4
• 硬化性胆管炎
• 自己免疫性膵炎
• 十二指腸主乳頭

Details

• CRID: 1390001204218270720
• NII Article ID: 10029092708
• NII Book ID: AN00192102
• DOI: 10.11280/gee.53.1617
• ISSN: 18845738
• ISSN: 03871207
• Web Site: https://search.jamas.or.jp/link/ui/2011281817
• Text Lang: ja
• Data Source:
  • JaLC
  • CiNii Articles
  • Crossref
• Abstract License Flag: Disallowed