Significance of the Anatomical Properties of a Myocardial Bridge in Coronary Heart Disease

• Ishikawa Yukio

  Department of Pathology, Toho University School of Medicine

• Kawawa Yoko

  Division of Diagnostic Radiology, National Cancer Center Hospital

• Kohda Eiichi

  Department of Radiology, Toho University Medical Center, Ohashi Hospital

• Shimada Kazuyuki

  Department of Neurology, Gross Anatomy Section, Kagoshima University Graduate School of Medical and Dental Sciences

• Ishii Toshiharu

  Department of Pathology, Toho University School of Medicine

抄録

A myocardial bridge (MB), partially covering the coronary artery, is a congenital anatomical variant usually present in the left anterior descending coronary artery (LAD). MB causes coronary heart disease (CHD) by 2 distinct mechanisms influenced by the anatomical properties of the MB, such as its length, thickness, and location. One is direct MB compression of the LAD at cardiac systole, resulting in delayed arterial relaxation at diastole, reduced blood flow reserve, and decreased blood perfusion. The other is enhancement of coronary atherosclerosis causing stenosis of the LAD proximal to the MB, occurring because of endothelial injury arising from the abnormal hemodynamics provoked by retrograde blood flow up toward the left coronary ostium at cardiac systole. The magnitude of the effect of the 2 distinct mechanisms of the MB on LAD blood flow is prescribed by a common root of the MB-muscle mass volume generated by those properties. Furthermore, the anatomical properties of the MB are closely associated with the choice of treatment and therapeutic outcome in CHD patients having an MB. Thus, the anatomical properties of an MB should be considered in the diagnosis and management of CHD patients with this anomaly. (Circ J 2011; 75: 1559-1566)<br>

収録刊行物

• Circulation Journal

  Circulation Journal 75 (7), 1559-1566, 2011

  一般社団法人 日本循環器学会

キーワード

• Anatomy
• Atherosclerosis
• Coronary heart disease
• Myocardial bridge

詳細情報

• CRID: 1390282680080514048
• NII論文ID: 10029126127
• NII書誌ID: AA11591968
• DOI: 10.1253/circj.cj-10-1278
• COI: 1:STN:280:DC%2BC3MnivFekug%3D%3D
• ISSN: 13474820
• ISSN: 13469843
• PubMed: 21467656
• Web Site: http://www.jstage.jst.go.jp/article/circj/75/7/75_CJ-10-1278/_pdf
• Web Site: https://search.jamas.or.jp/link/ui/2012001376
• 本文言語コード: en
• データソース種別:
  • JaLC
  • Crossref
  • PubMed
  • CiNii Articles
  • KAKEN
• 抄録ライセンスフラグ: 使用不可