Inhibitory Effects of Extracts from Citrus unshiu Marc. Encapsulated in Hybrid Liposomes on the Growth of Tumor Cells in Vitro

• Ueoka Hidetsugu

  Division of Applied Life Science, Graduate School of Engineering, Sojo University

• Komizu Yuji

  Division of Applied Life Science, Graduate School of Engineering, Sojo University

• Goto Koichi

  Division of Applied Life Science, Graduate School of Engineering, Sojo University

• Ueoka Ryuichi

  Division of Applied Life Science, Graduate School of Engineering, Sojo University

Bibliographic Information

Other Title

• 温州みかん抽出物含有ハイブリッドリポソームの制がん効果に関する研究
• ウンシュウ ミカン チュウシュツブツ ガンユウ ハイブリッド リポソーム ノ セイガン コウカ ニ カンスル ケンキュウ

Abstract

Inhibitory effects of extracts from fruits and fruit juices of Citrus unshiu Marc. (Unshiumikan) encapsulated in hybrid liposomes (HL) composed of L-α-dimyristoylphosphatidylcholine (DMPC) and polyoxyethylene(20) sorbitan monooleate (Tween 80) on the growth of tumor cells were examined in vitro. The extracts with lower polar solvents significantly inhibited the growth of human hepatoma (HuH-7) cells and human stomach cancer (MKN-45) cells, though the extracts with higher polar solvents showed no or little antitumor activity. These results suggest that hydrophobic antitumor compounds are present in fruits and fruit juices of Unshiumikan.

Journal

• KAGAKU KOGAKU RONBUNSHU

  KAGAKU KOGAKU RONBUNSHU 37 (3), 271-276, 2011

  The Society of Chemical Engineers, Japan

Keywords

• <i>Citrus unshiu</i> Marc.
• Antitumor Effect
• Hybrid Liposomes
• Biomass

Details

• CRID: 1390001204512498560
• NII Article ID: 10029241754
• NII Book ID: AN00037234
• DOI: 10.1252/kakoronbunshu.37.271
• ISSN: 13499203
• ISSN: 0386216X
• NDL BIB ID: 11188898
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I11188898
• Web Site: http://www.jstage.jst.go.jp/article/kakoronbunshu/37/3/37_3_271/_pdf
• Text Lang: ja
• Data Source:
  • JaLC
  • NDL
  • Crossref
  • CiNii Articles
  • KAKEN
• Abstract License Flag: Disallowed