Idiopathic Cardiomyopathies in Korean Children - 9-Year Korean Multicenter Study -

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  • Oh Jin Hee
    Department of Pediatrics, The Catholic University of Korea
  • Hong Young Mi
    Department of Pediatrics, School of Medicine, Ewha Womans University
  • Choi Jae Young
    Division of Pediatric Cardiology, Severance Cardiovascular Hospital, Yonsei University
  • Kim Soo Jin
    Department of Pediatrics, Sejong General Hospital
  • Jung Jo Won
    Department of Pediatrics, Ajou University
  • Sohn Sejung
    Department of Pediatrics, School of Medicine, Ewha Womans University
  • Hyun Myung Chul
    Department of Pediatrics, Kyungpook National University
  • Noh Chung Il
    Department of Pediatrics, Seoul National University
  • Lee Joo Won
    Department of Pediatrics, Korea University
  • Park In Sook
    Department of Pediatrics, Asan Medical Center, University of Ulsan

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タイトル別名
  • – 9-Year Korean Multicenter Study –

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Background: Idiopathic cardiomyopathies (CMPs) are an important heterogeneous group of diseases. With the advance of therapeutic strategies, epidemiologic data on CMP have become very important, but only a few have been reported in Asian children. We conducted a retrospective epidemiologic study of primary CMP in Korean children. Methods and Results: Using a multicenter survey, we studied primary CMP among Korean children from January 1998 to December 2006 based on classification (2006) of CMP by the American Heart Association. A total of 277 primary CMP patients were reported from 17 cardiovascular centers. The average annual occurrence of new cases of primary CMP was 0.28 per 100,000 Korean children younger than 15 years of age (95% confidence interval (CI) 0.24-0.31). Dilated CMP (DCMP) was 66.43%, hypertrophic CMP (HCMP) 23.47%, restrictive CMP (RCMP) 6.50% and others 3.61%. The point prevalence of primary CMP at the end of the study was estimated as 2.11/100,000 (95%CI 1.83-2.43), DCMP 1.39/100,000, HCMP 0.51/100,000, RCMP 0.16/100,000 and others 0.04/100,000. Survival rates over 9 years were 69.8% in DCMP, 90.3% in HCMP, and 47.2% in RCMP. Conclusions: Recent point prevalence of childhood primary CMP in Korea was estimated as 2.11/100,000. Further epidemiologic study with a nationwide survey is necessary. (Circ J 2011; 75: 2228-2234)<br>

収録刊行物

  • Circulation Journal

    Circulation Journal 75 (9), 2228-2234, 2011

    一般社団法人 日本循環器学会

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