Concurrent presentation of cryptococcal meningoencephalitis and systemic lupus erythematosus

• Matsumura, Masami

• Kawamura, Rika

• Inoue, Ryo

• Kawano, Mitsuhiro

• Yamagishi, Masakazu

抄録

金沢大学医薬保健研究域医学系医学教育研究センター

Cryptococcal meningitis is a recognized complication of systemic lupus erythematosus (SLE), with high mortality rates, particularly in those treated with immunosuppressive agents. We describe a patient diagnosed simultaneously with cryptococcal meningoencephalitis and SLE and reviewed four similar cases reported in the literature. In our case, profound low CD4 lymphocyte count and low complement levels were observed. The patient was treated with prednisolone, fluconazole, and 5-flucytosine and evinced good clinical improvement. This case suggests that intrinsic immunological abnormality related to SLE predisposed to opportunistic infections. © 2010 Japan College of Rheumatology.

収録刊行物

• Modern Rheumatology

  Modern Rheumatology 21 (3), 305-308, 2011-06-01

  Japan College of Rheumatology = 日本リウマチ学会 / Springer Verlag (Germany)

キーワード

• Cryptococcal meningoencephalitis
• Intrinsic immunological abnormality
• Systemic lupus erythematosus

詳細情報

• CRID: 1050282810927543808
• NII論文ID: 10029362350
• NII書誌ID: AA1157187X
• ISSN: 14397595
• Web Site: http://hdl.handle.net/2297/29569
• Web Site: https://search.jamas.or.jp/link/ui/2012137295
• 本文言語コード: en
• 資料種別: journal article
• データソース種別:
  • IRDB
  • CiNii Articles