Safety and Efficacy of Exercise Training After Coronary Stenting in Patients With Stable Coronary Artery Disease
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- Soga Yoshimitsu
- Department of Cardiology, Kokura Memorial Hospital
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- Yokoi Hiroyoshi
- Department of Cardiac Rehabilitation, Kokura Memorial Hospital
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- Amemiya Kisaki
- Department of Cardiology, Kokura Memorial Hospital
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- Iwabuchi Masashi
- Department of Cardiology, Kokura Memorial Hospital
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- Nobuyoshi Masakiyo
- Department of Cardiology, Kokura Memorial Hospital
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Background: Exercise training (ET) after coronary stenting is considered to have a risk of stent thrombosis (ST). The present study investigated whether ET increases the incidence of ST in patients undergoing coronary stenting. Methods and Results: The current study was a prospective observational study. We enrolled 3,672 patients who underwent successful coronary stenting. Patients decided whether to participate in exercise and were divided into an ET group (n=1,592) and a control group (n=2,080). The primary endpoint was the incidence of ST. Secondary endpoints were major adverse cardiovascular events (MACE: death, myocardial infarction, and stroke) and unscheduled hospital visits for angina. The incidence of ST and MACE were similar in both groups (1.8% vs. 2.0%, P=0.73, 14.9% vs. 15.0%, P=0.97, respectively). Unscheduled hospital visits were significantly lower in the ET group (20.2% vs. 27.2%, P<0.0001). After adjusting for baselines, the ET group had no significant increase in ST (hazard ratio (HR) 0.86, adjusted P=0.56) and MACE (HR 0.98, adjusted P=0.83). The ET was effective to prevent an unscheduled hospital visits for worsening angina (HR 0.67, adjusted P<0.0001). Conclusions: Moderate ET after successful coronary stenting does not increase the incidence of ST and MACE, and was effective in reducing unscheduled hospital visits for angina. (Circ J 2011; 75: 2379-2386)<br>
収録刊行物
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- Circulation Journal
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Circulation Journal 75 (10), 2379-2386, 2011
一般社団法人 日本循環器学会
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詳細情報 詳細情報について
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- CRID
- 1390282680078740096
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- NII論文ID
- 10029459399
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- NII書誌ID
- AA11591968
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- ISSN
- 13474820
- 13469843
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- 本文言語コード
- en
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- データソース種別
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- JaLC
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- 使用不可