核‐細胞質間高分子輸送の構造生物学

• 松浦 能行

  名古屋大学大学院理学研究科

書誌事項

タイトル別名

• Structural Biology of Macromolecular Transport into and out of the Cell Nucleus
• 核-細胞質間高分子輸送の構造生物学
• カク サイボウシツ カン コウブンシ ユソウ ノ コウゾウ セイブツガク

抄録

Active transport of macromolecules between the nucleus and the cytoplasm is mediated by transport receptors (carriers) that facilitate the passage of specific cargoes through the nuclear pore complexes. All of the nuclear transport pathways are based on a common principle: translocation across the nuclear pore appears to be reversible, and the directionality of transport depends on assembly of cargo-carrier complexes on one side of the nuclear envelope and disassembly of the transport complexes on the other side. This review highlights recent progress in understanding the structural basis of nuclear transport, especially in terms of CRM1-mediated nuclear export.<br>

収録刊行物

• 生物物理

  生物物理 51 (5), 208-213, 2011

  一般社団法人 日本生物物理学会

キーワード

• nuclear transport
• Ran GTPase
• importin
• exportin
• nuclear pore
• nucleoporin

詳細情報

• CRID: 1390282681511831680
• NII論文ID: 10029482414
• NII書誌ID: AN00129693
• DOI: 10.2142/biophys.51.208
• ISSN: 13474219
• ISSN: 05824052
• NDL書誌ID: 11259579
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I11259579
• Web Site: http://www.jstage.jst.go.jp/article/biophys/51/5/51_5_208/_pdf
• Web Site: https://search.jamas.or.jp/link/ui/2011354401
• 本文言語コード: ja
• データソース種別:
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  • NDL
  • Crossref
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• 抄録ライセンスフラグ: 使用不可