A Case of Undifferentiated Carcinoma of the Rectum

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  • NISHIMURA Junichi
    Department of Gastroenterology and Hepatology (Internal Medicine I.), Yamaguchi University Graduate School of Medicine
  • YANAI Hideo
    Department of Gastroenterology, National Hospital Organization Kanmon Medical Center
  • FURUYA Takumi
    Department of Surgery, National Hospital Organization Kanmon Medical Center
  • MURAKAMI Tomoyuki
    Department of Pathology, National Hospital Organization Kanmon Medical Center
  • HOASHI Seiji
    Hoashi Clinic
  • SAKAIDA Isao
    Department of Gastroenterology and Hepatology (Internal Medicine I.), Yamaguchi University Graduate School of Medicine

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Other Title
  • 直腸未分化癌の一例
  • チョクチョウ ミブンカ ガン ノ イチレイ
  • 症例報告 直腸未分化癌の一例
  • ショウレイ ホウコク チョクチョウ ミブンカガン ノ イチレイ

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Abstract

This is the case report of a 69-year-old female patient, who presented to a hospital due to melena as the chief complaint. A lower gastrointestinal endoscopy confirmed a 0IIc + IIa tumor found in the patient's lower rectum (Rb). On a biopsy, this patient was diagnosed with a squamous-cell carcinoma or an undifferentiated adenocarcinoma first. Upon the patient's strong request, a local excision of the rectum was performed as the medical treatment for this case. No duct-like structure was observed histologically in the surgical specimen, and the immunohistological detection did not confirm any mucoid secretion or endocrine granules. For these reasons, this patient was diagnosed with an undifferentiated carcinoma. Generally, undifferentiated carcinoma of the colon has a poor prognosis, thus early detection is desirable. However, there exist a number of unclear points in the initial picture of this carcinoma. This is to report our experience of this rare case, which is an example of undifferentiated carcinoma of the colorectal region.

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