甲状腺機能低下症における音声・構音障害と難聴

DOI Web Site 参考文献17件

書誌事項

タイトル別名
  • Hoarseness, Articulation Disorder and Hearing Impairment in Subjects with Hypothyroidism -Two Cases Hypothyroidism without Struma-
  • 臨床 甲状腺機能低下症における音声・構音障害と難聴 : 甲状腺腫を欠いた2例
  • リンショウ コウジョウセン キノウ テイカショウ ニ オケル オンセイ ・ コウオン ショウガイ ト ナンチョウ : コウジョウセンシュ オ カイタ 2レイ
  • Hoarseness, Articulation Disorder and Hearing Impairment in Subjects with Hypothyroidism
  • —Two Cases Hypothyroidism without Struma—

この論文をさがす

抄録

Thyroid hormones target cardiovascular, neuromuscular, digestive, and metabolic systems, meaning that hypothyroidism may cause a wide variety of symptoms. Hypothyroidism is usually characterized by struma and myxedema. The absence of struma, however, may cause hypothyroidism to be mistaken for other organ disorders or normal aging-associated change.<br> We report 2 cases of hypothyroidism without struma. Case 1 was a 76-year-old man seen for postnasal drip and ear stuffiness complicated by myocardial infarction, kidney dysfunction, and abnormally high CK. Case 2 was an 83-year-old man seen for prolonged dizziness, who also had heart failure and generalized edema. Neither patients responded well to a treatment and showed deteriorating truncal ataxia, increasing body weight, bradykinesia, bradyarthria, hoarseness, and impaired hearing. Case 2, also had edematous glottal change.<br> Although no struma was seen, thyroid hormone levels were measured to determine the cause of hoarseness, showing high TSH and low fT3 and fT4 level. Case 1 was diagnosed with primary hypothyroidism, and Case 2 with secondary hypothyroidism.<br> Hormonal therapy induced improvements in impaired hearing, previously considered a sign of aging, and in bradykinesia, truncal ataxia, and hoarseness. Hoarseness and bradyarthria were relieved regardless of glottal edema. Internal complications were also markedly alleviated. In case 1, impaired hearing worsened again after the mean stopped taking vitamin B12, but improved again when vitamin B12 was restarted.<br> Articulation disorder in hypothyroidism presumably involves neuropathy and affecting from speech center to articulatory organs, including the glottis. Impaired hearing also presumably is caused by the same neuropathy depending on the vitamin B12 level.<br>

収録刊行物

参考文献 (17)*注記

もっと見る

キーワード

詳細情報 詳細情報について

問題の指摘

ページトップへ