Microwave-Assisted Direct H/D Exchange Reactions of Dimetridazole and Metronidazole in Alkaline D₂O

• Akira Miyazawa

• Haruki Shimodaira

• Yuji Kawanishi

抄録

Upon microwave irradiation, a ring proton at the 4-position and protons at the 2-methyl positions of dimetridazole, 1,2-dimethyl-5-nitroimidazole, and metronidazole, 1-(2-hydroxyethyl)-2-methyl-5-nitroimidazole, were selectively and rapidly exchanged with deuterium at an exchange efficiency in excess of 98 atom % within 30 min.

収録刊行物

• Bulletin of the Chemical Society of Japan

  Bulletin of the Chemical Society of Japan 84 (12), 1368-1370, 2011-12

  Tokyo : Chemical Society of Japan

キーワード

• General Chemistry

詳細情報

• CRID: 1523106605167763072
• NII論文ID: 10030216676
• NII書誌ID: AA00580132
• ISSN: 00092673
• ISSN: 13480634
• DOI: 10.1246/bcsj.20110095
• NDL書誌ID: 023387792
• Web Site: http://id.ndl.go.jp/bib/023387792
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I023387792
• Web Site: https://academic.oup.com/bcsj/article-pdf/84/12/1368/56273097/bcsj.20110095.pdf
• 本文言語コード: en
• NDL 雑誌分類:
  • ZP1(科学技術--化学・化学工業)
• データソース種別:
  • NDL
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