Hyperparathyroidism due to Eutopic PTH Secretion from an Ectopic Intrathymic Parathyroid Cyst

• Hoi Wai Han

  Department of Endocrinology, Tan Tock Seng Hospital, Singapore

• Leow Melvin Khee-Shing

  Department of Endocrinology, Tan Tock Seng Hospital, Singapore

• Sule Ashish

  Department of General Medicine, Tan Tock Seng Hospital, Singapore

• Lee Hwei Yee

  Department of Pathology, Tan Tock Seng Hospital, Singapore

• Mmed T Agasthian

  Department of Surgical Oncology, National Cancer Center, Singapore

• Tay Jam Chin

  Department of Endocrinology, Tan Tock Seng Hospital, Singapore

抄録

Parathyroid cysts rarely cause hyperparathyroidism. In addition, they rarely occur in the thymus. We report a 56-year-old woman with hypertension on telmisartan and hydrochlorothiazide, who developed symptomatic hypercalcemia for a month. Initial serum calcium was 15.6 mg/dL, together with inappropriately elevated intact PTH at 437 pg/mL. Coincidentally, an anterior mediastinal mass on chest imaging was found. Biopsy of the mass revealed parathyroid tissue. She was treated sequentially with saline rehydration and frusemide calciuresis, intravenous pamidronate and calcitonin, which lowered her calcium to 11.1 mg/dL. Normocalcemia was finally achieved following surgical extirpation of the mass. Histology confirmed an intrathymic parathyroid cyst. Definitive treatment by resection of the mass is potentially curative.

収録刊行物

• Annals of Thoracic and Cardiovascular Surgery

  Annals of Thoracic and Cardiovascular Surgery 17 (5), 511-513, 2011

  Annals of Thoracic and Cardiovascular Surgery 編集委員会

キーワード

• mediastinal
• intrathymic
• parathyroid cyst
• hyperparathyroidism
• hypercalcemia

詳細情報

• CRID: 1390282679704926848
• NII論文ID: 10030235278
• NII書誌ID: AA11035352
• DOI: 10.5761/atcs.cr.10.01634
• ISSN: 21861005
• ISSN: 13411098
• Web Site: https://search.jamas.or.jp/link/ui/2012169869
• 本文言語コード: en
• データソース種別:
  • JaLC
  • Crossref
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可