Clinical impact of albuminuria in diabetic nephropathy

• Wada, Takashi

• Shimizu, Miho

• Toyama, Tadashi

• Hara, Akinori

• Kaneko, Shuichi

• Furuichi, Kengo

抄録

金沢大学医薬保健研究域医学系

Patients suffering from diabetic nephropathy, resulting in end-stage renal failure, are increasing in number. The pathophysiology of diabetic nephropathy remains to be fully investigated. In the clinical setting, the presence of albuminuria/overt proteinuria and a low glomerular filtration rate may predict poor renal prognosis, but the prognosis of the normoalbuminuric renally insufficient diabetic patient remains controversial. In addition to the measurement of urinary albumin excretion, biomarker studies to detect diabetic nephropathy more specifically at the early stage have been performed worldwide. There is a growing body of evidence for remission and/or regression of diabetic nephropathy, which may be an indicator for cardiovascular and renal risk reduction. Deeper insights into the pathological characteristics as well as the clinical impact of albuminuria on renal and cardiovascular outcome are required. © 2011 Japanese Society of Nephrology.

収録刊行物

• Clinical and Experimental Nephrology

  Clinical and Experimental Nephrology 16 (1), 96-101, 2012-02-01

  Springer Verlag (Germany) / Japanese Society of Nephrology

キーワード

• Albuminuria
• Cardiovascular disease
• Diabetic nephropathy
• Glomerular filtration rate
• Proteinuria
• Renal outcome

詳細情報

• CRID: 1050282810927513088
• NII論文ID: 10030342987
• NII書誌ID: AA11126935
• ISSN: 13421751
• Web Site: http://hdl.handle.net/2297/29219
• 本文言語コード: en
• 資料種別: journal article
• データソース種別:
  • IRDB
  • CiNii Articles