Anticoagulant Therapy in Pregnant Women with Thrombosis

• Yamada Tetsuya

  Department of Vascular Surgery, Aichi Medical University Hospital

• Ohta Takashi

  Department of Vascular Surgery, Aichi Medical University Hospital

• Ishibashi Hiroyuki

  Department of Vascular Surgery, Aichi Medical University Hospital

• Sugimoto Ikuo

  Department of Vascular Surgery, Aichi Medical University Hospital

• Iwata Hirohide

  Department of Vascular Surgery, Aichi Medical University Hospital

• Tadakoshi Masao

  Department of Vascular Surgery, Aichi Medical University Hospital

• Hida Noriyuki

  Department of Vascular Surgery, Aichi Medical University Hospital

• Orimoto Yuki

  Department of Vascular Surgery, Aichi Medical University Hospital

Bibliographic Information

Other Title

• 血栓症合併妊娠における抗凝固療法

Abstract

A 35-year-old female with swelling of the right lower limb in Week 9 of pregnancy was referred to our hospital. The coagulation marker level was abnormally high, and ultrasonography revealed thrombi in the right femoral and popliteal veins. Furthermore, the antithrombin (AT) activity and antigen level were reduced, suggesting pregnancy with AT deficiency-related thrombosis. As thrombosis exacerbated despite physical therapy, anticoagulant therapy was performed to control thrombosis. The thrombus involved the inferior vena cava, requiring IVC filter insertion. She delivered a baby in Week 38 of pregnancy via transvaginal delivery. There were no maternal or neonatal complications.<br>It is recommended that prophylactic drug therapy be started in the first trimester in pregnant women with a history of venous thrombosis or thrombophilia. In the present case, it was necessary to perform anticoagulant therapy after admission. On the other hand, admission-related mental stress for pregnant women is marked. Thrombosis control with non-fractional heparin subcutaneously injected at the outpatient clinic was useful. Although pregnant women with thrombosis comprise a high-risk group, it is possible to continue pregnancy through appropriate thrombosis control.

Journal

• The Japanese Journal of Phlebology

  The Japanese Journal of Phlebology 23 (1), 39-43, 2012

  Japanese Society of Phlebology

Keywords

• Venous thromboembolism
• Pregnancy
• Antithrombin deficiency
• Subcutaneous heparin injection

Details

• CRID: 1390001204369559936
• NII Article ID: 10030353119
• NII Book ID: AN10186004
• DOI: 10.7134/phlebol.23.39
• ISSN: 21865523
• ISSN: 09157395
• Web Site: https://search.jamas.or.jp/link/ui/2012175522
• Data Source:
  • JaLC
  • Crossref
  • CiNii Articles
• Abstract License Flag: Disallowed