書誌事項
- タイトル別名
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- Regulation of Ciliary Structure and Motility by Post-translational Modifications of Tubulin
- チューブリン ホンヤク ゴ シュウショク コウソ ニ ヨル センモウ ノ コウゾウ ・ ウンドウ セイギョ
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抄録
Post-translational modifications of proteins change dramatically and dynamically protein structures and functions. Tubulin, which forms microtubules, undergoes highly unique post-translational modifications, polyglutamylation and polyglycylation. These modifications, in particular, accumulate in the axoneme of cilia or flagella. Recently, we and others have identified enzymes that perform or reverse those modifications. The discovery of enzymes enables to investigate the physiological roles of the modifications by means of model organisms with knockout or knockdown techniques. We here review recent knowledge, focusing on our own findings, about the roles of polyglutamylation and polyglycylation in ciliary or flagellar structure and motility.<br>
収録刊行物
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- 生物物理
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生物物理 52 (4), 178-181, 2012
一般社団法人 日本生物物理学会
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詳細情報 詳細情報について
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- CRID
- 1390001206534212736
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- NII論文ID
- 10030494615
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- NII書誌ID
- AN00129693
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- COI
- 1:CAS:528:DC%2BC38XhtFOrt7jL
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- ISSN
- 13474219
- 05824052
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- NDL書誌ID
- 023910214
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- 本文言語コード
- ja
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- データソース種別
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- JaLC
- NDL
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- 抄録ライセンスフラグ
- 使用不可