Application of Optical Coherence Tomography in Percutaneous Coronary Intervention

• Kubo Takashi

  Department of Cardiovascular Medicine, Wakayama Medical University

• Tanaka Atsushi

  Department of Cardiovascular Medicine, Wakayama Medical University

• Kitabata Hironori

  Department of Cardiovascular Medicine, Wakayama Medical University

• Ino Yasushi

  Department of Cardiovascular Medicine, Wakayama Medical University

• Tanimoto Takashi

  Department of Cardiovascular Medicine, Wakayama Medical University

• Akasaka Takashi

  Department of Cardiovascular Medicine, Wakayama Medical University

抄録

Optical coherence tomography (OCT) is a high resolution imaging technique that offers microscopic visualization of the coronary artery. The fast scanning speed and simple imaging procedure of new-generation frequency-domain OCT make this technology easy to use in the clinical setting. The OCT examination is useful for guidance and risk stratification of percutaneous coronary intervention (PCI). OCT-derived thin-cap fibroatheroma, which is characterized by large lipid-core and thin fibrous cap <65μm, is a predictor of peri-PCI complications, such as angiographic no-reflow, microvascular obstruction, and post-PCI cardiac troponin I elevation. Stent malapposition, tissue protrusion, and stent edge dissection are assessed in more detail by OCT than with conventional intravascular imaging modalities. Neointimal coverage at strut level assessed by OCT could be a surrogate endpoint for quickly scrutinizing safety after drug-eluting stent implantation. The OCT findings of in-stent neoatherosclerosis, such as lipid-rich neointima, microvascular proliferation, and neointimal plaque rupture, are associated with very late stent failure, including thrombosis and restenosis. With its excellent ability to assess coronary atherosclerosis and to guide PCI, OCT provides new insights into interventional cardiology.  (Circ J 2012; 76: 2076–2083)<br>

収録刊行物

• Circulation Journal

  Circulation Journal 76 (9), 2076-2083, 2012

  一般社団法人 日本循環器学会

キーワード

• Drug-eluting stents
• Optical coherence tomography
• Percutaneous coronary intervention

詳細情報

• CRID: 1390282680079414144
• NII論文ID: 10030696229
• NII書誌ID: AA11591968
• DOI: 10.1253/circj.cj-12-0828
• COI: 1:STN:280:DC%2BC38fksV2ksg%3D%3D
• ISSN: 13474820
• ISSN: 13469843
• PubMed: 22850338
• Web Site: https://www.jstage.jst.go.jp/article/circj/76/9/76_CJ-12-0828/_pdf
• Web Site: https://search.jamas.or.jp/link/ui/2013306595
• 本文言語コード: en
• データソース種別:
  • JaLC
  • Crossref
  • PubMed
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可