書誌事項
- タイトル別名
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- A case of a syndrome of inappropriate antidiuretic hormone secretion and central pontine myelinolysis after chemotherapy for oral cancer
- コウコウガン カガク リョウホウ ゴ ニ コウリニョウ ホルモン フテキゴウ ブンピ ショウコウグン ト ハシ チュウ シンズイ サヤ ユウカイ オ ヘイハツ シタ 1レイ
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We report a case with marked serum electrolytic disorders, a syndrome of inappropriate antidiuretic hormone secretion (SIADH) and central pontine myelinolysis (CPM) following systemic chemotherapy using cisplatin (CDDP).<br>The patient was a 66-year-old man with squamous cell carcinoma of the tongue and floor of the mouth at the clinical stage rT4N0M0. He was receiving combination chemotherapy with CDDP, docetaxel and 5-FU. Marked hyponatremia appeared within 2 days of the chemotherapy. Furthermore, increases in the antidiuretic hormone level, plasma osmolality, urinary osmolality and urine Na concentration were identified. Finally, SIADH was diagnosed. Water intake was limited and supplementary Na was provided, improving hyponatremia. CPM appeared following correction of the serum Na concentration, but resolved spontaneously over time.<br>We consider that serum sodium should be measured frequently after chemotherapy including CDDP and that an early response is important when hyponatremia occurs.
収録刊行物
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- 日本口腔科学会雑誌
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日本口腔科学会雑誌 61 (2), 237-242, 2012
特定非営利活動法人 日本口腔科学会
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詳細情報 詳細情報について
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- CRID
- 1390282681413146368
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- NII論文ID
- 130004555772
- 10030795857
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- NII書誌ID
- AN00189050
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- ISSN
- 21850461
- 00290297
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- NDL書誌ID
- 023744937
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- NDL
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可