気管支顆粒細胞腫の 2 例

  • 鈴木 奈緒子
    がん研究会有明病院細胞診断部
  • 星 利良
    がん研究会有明病院細胞診断部
  • 古田 則行
    がん研究会有明病院細胞診断部
  • 杉山 裕子
    がん研究会有明病院細胞診断部
  • 佐藤 之俊
    がん研究会有明病院細胞診断部 北里大学医学部呼吸器外科学 がん研究会がん研究所病理部
  • 元井 紀子
    がん研究会有明病院細胞診断部 がん研究会がん研究所病理部
  • 石川 雄一
    がん研究会がん研究所病理部
  • 宝来 威
    がん研究会有明病院細胞診断部 がん研究会有明病院呼吸器内科

書誌事項

タイトル別名
  • Bronchial granular cell tumor—a report of two cases—

この論文をさがす

抄録

Background : Granular cell tumors located in the bronchus are rarely found, and the cytologic features of this tumor have not been reported. We present two cases of bronchial granular cell tumor, which had differences in nuclear pleomorphism.<br>Cases : In both cases (Case 1 : 45-year-old female, Case 2 : 37-year-old male), a nodule was revealed in the right upper lobe on computerized tomography imaging. A cytologic diagnosis was difficult with samples from transbronchial aspiration, but the histologic diagnosis was a granular cell tumor based on the transbronchial biopsy. A lobectomy was performed for both cases. Imprint cytologic smears obtained from resected specimens revealed many tumor cells with abundant and granular cytoplasm. The cytologic specimens from Case 1 showed uniform tumor cells, whereas, the specimens obtained from Case 2 showed a variety of tumor cells with large and/or spindle nuclei, which suggested the possibility of malignancy. Histologically, both the tumors were diagnosed as a granular cell tumor, and the tumor cells were immunohistochemically positive for S-100 protein.<br>Conclusion : Focusing on abundant and granular cytoplasm could allow us to make the correct diagnosis of granular cell tumor although the nuclear features varied from case to case : some having large and/or spindle nuclei.

収録刊行物

参考文献 (18)*注記

もっと見る

詳細情報 詳細情報について

問題の指摘

ページトップへ