書誌事項
- タイトル別名
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- Bronchial granular cell tumor—a report of two cases—
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Background : Granular cell tumors located in the bronchus are rarely found, and the cytologic features of this tumor have not been reported. We present two cases of bronchial granular cell tumor, which had differences in nuclear pleomorphism.<br>Cases : In both cases (Case 1 : 45-year-old female, Case 2 : 37-year-old male), a nodule was revealed in the right upper lobe on computerized tomography imaging. A cytologic diagnosis was difficult with samples from transbronchial aspiration, but the histologic diagnosis was a granular cell tumor based on the transbronchial biopsy. A lobectomy was performed for both cases. Imprint cytologic smears obtained from resected specimens revealed many tumor cells with abundant and granular cytoplasm. The cytologic specimens from Case 1 showed uniform tumor cells, whereas, the specimens obtained from Case 2 showed a variety of tumor cells with large and/or spindle nuclei, which suggested the possibility of malignancy. Histologically, both the tumors were diagnosed as a granular cell tumor, and the tumor cells were immunohistochemically positive for S-100 protein.<br>Conclusion : Focusing on abundant and granular cytoplasm could allow us to make the correct diagnosis of granular cell tumor although the nuclear features varied from case to case : some having large and/or spindle nuclei.
収録刊行物
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- 日本臨床細胞学会雑誌
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日本臨床細胞学会雑誌 51 (5), 354-359, 2012
公益社団法人 日本臨床細胞学会
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詳細情報 詳細情報について
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- CRID
- 1390282679674040192
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- NII論文ID
- 10030873952
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- NII書誌ID
- AN00198721
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- ISSN
- 18827233
- 03871193
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- 本文言語コード
- ja
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- データソース種別
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- JaLC
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- 使用不可