肝動注化学療法により減黄を示したにもかかわらず腫瘍の増大を呈した肝内胆管癌の1剖検例

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タイトル別名
  • A case of unresectable intrahepatic cholangiocarcinoma that presented an increase of tumor size in spite of having shown an improvement of jaundice by hepatic arterial infusion chemotherapy

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A-60-year-old male had diagnosed as unresectable intrahepatic cholangiocarcinoma (ICC) with dilation of intrahepatic bile duct in left lobe. Angiography showed an encasement of proper hepatic artery (PHA) The reservoir catheter was inserted into PHA for hepatic arterial infusion chemotherapy (HAIC) using 5-FU and CDDP. The jaundice was getting to diminish with a reduction of the dilated right intrahepatic bile duct with HAIC, however, the ICC increased in size and accounted for most of left hepatic lobe. Then, the angiography through the reservoir catheter showed complete obstruction of PHA. He was complicated by sepsis, and died after hospitalization on the 65 th day. Autopsy specified that ICC which was histologically moderately to poorly differentiated adenocarcinoma, occupied the majority of only left lobe. PHA and left portal vein oppacified tumor emboli without dilation of intrahepatic bile duct.

収録刊行物

  • Tando

    Tando 18 (1), 74-80, 2004

    Japan Biliary Association

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