ぶどうジュースを用いた内視鏡下胃液pH評価の検討 Endoscopic pH Evaluation of Fasting Gastric juice with Grape Juice

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【背景・目的】内視鏡による胃液pH検査は酸関連疾患の研究にしばしば用いられる.ぶどうジュースにはpHにより色調が変化する色素が含まれており,これを利用した内視鏡による胃液pHの評価を試みた.<BR>【方法】咽頭麻酔時にぶどうジュースを投与し前処置をおこなった.その後内視鏡検査時にモニターでの胃液の色調評価,胃液の採取およびpH測定を行った.<BR>【結果】胃液の色調は赤色,黒青色,透明~白色,黄色の4つに分類した.黄色と透明~白色以外のすべての色間でpH値は有意差を示した.赤色および透明~白色では酸性であり,黒青色は弱酸性から中性であった.<BR>【結論】胃液pH測定は胃酸関連疾患の病態生理を知るうえで有意義である.本法により容易かつ安全に多くの症例で大まかな胃液pHの評価が可能である.

Background : The pH measurement of fasting gastric juice is often used to investigate acid-related disorders. Grape juice contains anthocyanin pigments that change color according to the pH. The aim of this study was to evaluate the pH of fasting gastric juice with grape juice. Methods : Before the upper endoscopy, pharyngeal anesthesia was achieved with a frozen mixture of viscous lidocaine and grape juice, which the patient licked to ingest. During the upper endoscopy the colors of the gastric juice on the LCD monitor were evaluated. The gastric juice was serially collected and the pH of the gastric juice was evaluated. Results : The colors of the gastric juice were classified into four groups of red, blackish-blue, clear-white and yellow. Red and clear-white groups showed a low pH. The blackish-blue group showed weak acid to neutral pH. The yellow group showed no specific pH. The pH values of each pair of groups except for yellow and clear-white showed significant differences. Conclusions : The pH values of gastric juice are useful to realize the pathophysiology of acid-related disorders. Using this method, in most of cases we can easily determine the approximate intragastric acidity.

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  • 日本消化器内視鏡学会雑誌 = Gastroenterological endoscopy

    日本消化器内視鏡学会雑誌 = Gastroenterological endoscopy 54(6), 1853-1857, 2012-06-20

    Japan Gastroenterological Endoscopy Society

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各種コード

  • NII論文ID(NAID)
    10030961435
  • NII書誌ID(NCID)
    AN00192102
  • 本文言語コード
    JPN
  • 資料種別
    NOT
  • ISSN
    03871207
  • データ提供元
    CJP書誌  J-STAGE 
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