難治性感染に対する抗菌縫合糸使用の小経験

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タイトル別名
  • A Study of Surgical Treatment for Severe Bone and Joint Infections with Antibacterial Sutures

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The infection at surgical sites is a major problem in surgical patients. It was found that sutures play a role in surgical site infection. Due to the importance of suture, suture coated with Triclosan was developed. Triclosan is a broad-spectrum antiseptic and has been used for over 30 years. It has antimicrobial activity against S. aureus, S. epidermidis, MRSA, MRSE, Vancomycin resistant Enterococcus fecalis, Psedomonas aeruginosa and E.coli. Polyglactin 910 (Vicryl), a commonly used suture, is coated with Triclosan and is sold under the trade name of Vicryl Plus. Vicryl Plus has been used in veterinary practice and was found to be effective in prevention of surgical site infection. However, there were reports on tissue reaction caused by Vicryl and Vicryl Plus.These reactions happened rarely and equally between Vicryl and Vicryl Plus, suggesting that it was not caused by Triclosan but probably resulted from a contamination.

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