MR Characterization of Focal Nodular Hyperplasia: Gadoxetic Acid versus Superparamagnetic Iron Oxide Imaging

• SAITO Kazuhiro

  Department of Radiology, Tokyo Medical University

• YOSHIMURA Nobutaka

  Department of Radiology, Tokyo Medical University

• SAGUCHI Toru

  Department of Radiology, Tokyo Medical University

• PARK Jinho

  Department of Radiology, Tokyo Medical University

• SUGIMOTO Katsutoshi

  Department of Gastroenterology and Hepatology, Tokyo Medical University

• AKATA Soichi

  Department of Radiology, Tokyo Medical University

• MORIYASU Fuminori

  Department of Gastroenterology and Hepatology, Tokyo Medical University

• TOKUUYE Koichi

  Department of Radiology, Tokyo Medical University

抄録

Purpose: We evaluated the diagnostic efficacy of gadoxetic acid- and superparamagnetic iron oxide (SPIO)-enhanced magnetic resonance (MR) imaging for focal nodular hyperplasia (FNH).<br> Materials and Methods: We retrospectively evaluated 11 patients with 11 FNHs. Both gadoxetic acid- and SPIO-enhanced MR imaging were performed. A 3-dimensional (3D) volumetric interpolated breath-hold examination was used with the gadoxetic acid dynamic study. SPIO-enhanced MR imaging included T₂- and T₂*-weighted images. We quantitatively and qualitatively compared lesion-specific enhancement of both contrast media.<br> Results: The mean signal-to-noise (S/N) ratio of the FNH lesions differed significantly on pre- and postenhanced imaging of each contrast medium (P<0.05); mean contrast-to-noise (C/N) ratio did not (P>0.05). All observers described all lesions as hyperintense in the arterial phase on gadoxetic acid-enhanced MR imaging and observed the presence of central scar, fibrous septa, and rim most clearly in gadoxetic acid-enhanced hepatobiliary phase images.<br> Conclusion: Gadoxetic acid-enhanced MR imaging was more useful than SPIO-enhanced MR imaging in characterizing FNH.<br>

収録刊行物

• Magnetic Resonance in Medical Sciences

  Magnetic Resonance in Medical Sciences 11 (3), 163-169, 2012

  日本磁気共鳴医学会

キーワード

• focal nodular hyperplasia
• gadolinium ethoxybenzyl diethylenetriamine pentaacetic acid
• gadoxetic acid
• magnetic resonance imaging
• superparamagnetic iron oxide

詳細情報

• CRID: 1390001205196220544
• NII論文ID: 10031046811
• NII書誌ID: AA11648770
• DOI: 10.2463/mrms.11.163
• COI: 1:STN:280:DC%2BC3s%2Fis1eitg%3D%3D
• ISSN: 18802206
• ISSN: 13473182
• PubMed: 23037560
• Web Site: https://www.jstage.jst.go.jp/article/mrms/11/3/11_163/_pdf
• Web Site: https://search.jamas.or.jp/link/ui/2013306738
• 本文言語コード: en
• データソース種別:
  • JaLC
  • Crossref
  • PubMed
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可