術後早期に胸膜播種をきたした肉腫様変化を伴う肝細胞癌の1例

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タイトル別名
  • A Case of Hepatocellular Carcinoma with Sarcomatous Change Showing Rapid Recurrence in Pleural Dissemination after Hepatectomy
  • ショウレイ ホウコク ジュツゴ ソウキ ニ キョウマク ハシュ オ キタシタ ニクシュ ヨウ ヘンカ オ トモナウ カン サイボウガン ノ 1レイ

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We report a case of hepatocellular carcinoma with sarcomatous change that rapidly recurred in pleural dissemination after hepatectomy. A 61-year-old man was diagnosed as having a hepatic mass. Hepatocellular carcinoma accompanied by multiple intrahepatic metastases was diagnosed based on computed tomography and magnetic resonance imaging. Extended right hepatic lobectomy under thoracolaparotomy was performed after portal vein embolization. Forty days after hepatectomy, the patient was complicated with massive pleural effusion. Thoracoscopy showed diffuse irregular thickened pleura, in which, spindle cells positive for Vimentin, Keratin and EMA were demonstrated. Same type spindle cells were recognized around hepatocellular carcinoma in the liver. Final diagnosis of hepatocellular carcinoma with sarcomatous change was made. The patient died 56 days after hepatectomy. Close follow-up is needed in cases of hepatocellular carcioma with sarcomatous change, because the carcinoma has a strong potential for recurrence such as dissemination. <br>

収録刊行物

  • 肝臓

    肝臓 53 (11), 769-778, 2012

    一般社団法人 日本肝臓学会

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