Late Cardiac Remodeling After Primary Percutaneous Coronary Intervention
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- Springeling Tirza
- Department of Radiology, Erasmus Medical Center Department of Cardiology, Erasmus Medical Center
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- Kirschbaum Sharon W.
- Department of Cardiology, Erasmus Medical Center Department of Radiology, Erasmus Medical Center
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- Rossi Alexia
- Department of Radiology, Erasmus Medical Center Department of Cardiology, Erasmus Medical Center
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- Baks Timo
- Department of Cardiology, Erasmus Medical Center
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- Karamermer Yusuf
- Department of Radiology, Erasmus Medical Center
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- Schulz Carl
- Department of Cardiology, Erasmus Medical Center
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- Ouhlous Mohammed
- Department of Radiology, Erasmus Medical Center
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- Duncker Dirk J.
- Department of Cardiology, Erasmus Medical Center
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- Moelker Adriaan
- Department of Radiology, Erasmus Medical Center
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- Krestin Gabriel P.
- Department of Radiology, Erasmus Medical Center
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- Serruys Patrick W.J.C.
- Department of Cardiology, Erasmus Medical Center
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- de Feyter Pim
- Department of Radiology, Erasmus Medical Center Department of Cardiology, Erasmus Medical Center
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- van Geuns Robert-Jan M.
- Department of Radiology, Erasmus Medical Center Department of Cardiology, Erasmus Medical Center
書誌事項
- タイトル別名
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- – Five-Year Cardiac Magnetic Resonance Imaging Follow-up –
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Background: Primary percutaneous coronary intervention (PPCI) preserves function and improves survival. The late effects of PPCI on left ventricular remodeling, however, have not yet been investigated on cardiac magnetic resonance imaging (CMRI). Methods and Results: Twenty-five patients with acute myocardial infarction (AMI) treated with PPCI underwent CMRI within 10 days, at 4 months and at 5 years. Left ventricular ejection fraction (LVEF), end-diastolic volume (EDV) and end-systolic volume were quantified on cine images. Infarct mass and transmural extent of infarction were quantified on contrast-enhanced imaging. In all patients EDV increased significantly in the early phase (192±40ml to 211±49ml, P≤0.01) and LVEF improved significantly (42±9% to 46±9%, P=0.02). In the late phase (>4 months) no significant changes were observed (LVEF 44±9%, P=0.07; EDV 216±68ml, P=0.38). Three different groups could be identified. One-third (32%) had no dilatation at all; one-third (32%) had limited dilatation at 4 months without progression later; and 36% had progressive dilatation both at 4 months and at late follow-up. This third group had an average increase in EDV of 20% in the acute phase followed by an additional 13%. The strongest predictor for progressive dilatation was infarct mass. Conclusions: Even in the era of PPCI for AMI followed by optimal medical therapy, one-third of patients had progressive dilatation, which was best predicted by infarct mass. (Circ J 2013; 77: 81–88)<br>
収録刊行物
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- Circulation Journal
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Circulation Journal 77 (1), 81-88, 2013
一般社団法人 日本循環器学会
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詳細情報 詳細情報について
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- CRID
- 1390282680080652672
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- NII論文ID
- 10031131571
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- NII書誌ID
- AA11591968
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- COI
- 1:STN:280:DC%2BC3s%2FgslOmsw%3D%3D
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- ISSN
- 13474820
- 13469843
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- PubMed
- 23018679
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- Crossref
- PubMed
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- 使用不可