Cleavage of Supercoiled Plasmid DNA by Phenanthroline–Polyamine Conjugates as a Metal-free Artificial Nuclease

• Masuda Tomokazu

  Department of Chemistry and Chemical Biology, Graduate School of Engineering, Gunma University

• Sasagase Takeshi

  Department of Chemistry and Chemical Biology, Graduate School of Engineering, Gunma University

• Ozaki Akiko N.

  Department of Chemistry and Chemical Biology, Graduate School of Engineering, Gunma University

• Kuwahara Masayasu

  Department of Chemistry and Chemical Biology, Graduate School of Engineering, Gunma University

• Ozaki Hiroaki

  Department of Chemistry and Chemical Biology, Graduate School of Engineering, Gunma University

• Sawai Hiroaki

  Department of Chemistry and Chemical Biology, Graduate School of Engineering, Gunma University

抄録

In this study, phenanthroline–polyamine conjugates have been synthesized. The conjugates bind to DNA and hydrolyze it in the absence of any metal and reducing agent under physiological conditions.

収録刊行物

• Chemistry Letters

  Chemistry Letters 42 (1), 86-88, 2013

  公益社団法人 日本化学会

キーワード

• General Chemistry

詳細情報

• CRID: 1390282679565661568
• NII論文ID: 10031143809
• NII書誌ID: AA00603318
• DOI: 10.1246/cl.2013.86
• COI: 1:CAS:528:DC%2BC3sXitVelurg%3D
• ISSN: 13480715
• ISSN: 03667022
• Web Site: https://academic.oup.com/chemlett/article-pdf/42/1/86/55637709/cl.2013.86.pdf
• 本文言語コード: en
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