Occult HBV感染と考えられる血液製剤による輸血後B型急性肝炎の一例

• 山下 信行

  新小倉病院肝臓病センター

• 谷本 博徳

  新小倉病院肝臓病センター

• 野村 秀幸

  新小倉病院肝臓病センター

書誌事項

タイトル別名

• A case of post-transfusion hepatitis by an occult HBV carrier
• ショウレイ ホウコク Occult HBV カンセン ト カンガエラレル ケツエキ セイザイ ニ ヨル ユケツ ゴ Bガタ キュウセイ カンエン ノ イチレイ

抄録

We report a case of acute hepatitis B caused by blood transfusion. The case is a male patient of 50s who underwent cardiac operation. Hepatitis B surface (HBs) antigen, HBs antibody and HB core antibody were all negative at 80 days after the transfusion but the liver function tests became abnormal at 6 months. HBs antigen and HBV-DNA turned positive and he was diagnosed as having acute hepatitis B. He recovered without antiviral therapies and HBV-DNA became negative within several weeks. HBV-DNA was detected in a pack of used fresh-frozen plasma. The nucleic acid sequence of HBV was matched with that obtained from the patient. The blood donor had frequently performed blood donation and this case is considered as occult HBV infection. Several cases of post-transfusion type B hepatitis are occurring every year in Japan in spite of improvement of a nucleic acid amplification test.<br>

収録刊行物

• 肝臓

  肝臓 54 (1), 60-66, 2013

  一般社団法人　日本肝臓学会

キーワード

• 輸血後肝炎
• B型急性肝炎
• Occult HBV感染（OBI）
• 核酸増幅検査（NAT）
• ウイルス塩基配列

詳細情報

• CRID: 1390001204794059264
• NII論文ID: 10031144321
• NII書誌ID: AN00047770
• DOI: 10.2957/kanzo.54.60
• ISSN: 18813593
• ISSN: 04514203
• NDL書誌ID: 024214855
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I024214855
• Web Site: https://www.jstage.jst.go.jp/article/kanzo/54/1/54_60/_pdf
• Web Site: https://search.jamas.or.jp/link/ui/2013152004
• 本文言語コード: ja
• データソース種別:
  • JaLC
  • NDL
  • Crossref
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可