動脈硬化の進行に伴う皮膚灌流圧（SPP）の変化

• 原 道顯

  原内科クリニック

書誌事項

タイトル別名

• Changes in the observed variable of skin perfusion pressure (SPP) testing in correlation with the progression of arteriosclerosis
• ドウミャク コウカ ノ シンコウ ニ トモナウ ヒフカンリュウアツ(SPP)ノ ヘンカ

抄録

The skin perfusion pressure (SPP) in the plantae declines in dialysis patients with peripheral artery disease, but also varies according to a patient's blood pressure at the time of measurement. A decline in SPP is also seen among those in good health. In this study, SPP was measured between the base of the first and second toes on both the left and right feet of 105 healthy persons and 78 dialysis patients, and factors that influenced the measured SPP were evaluated. These factors were broadly categorized into: 1) measurement factors that varied with every measurement, 2) arteriosclerotic factors that varied with each patient. The measurement factors used were the upper arm systolic blood pressure and pulse, and the arteriosclerotic factors used were the arteriosclerotic risk factor (model 1) and arteriosclerotic test max-IMT in the common carotid artery (model 2). Independence between the elements which comprise each factor was assumed. Any relation between the two explanatory SPP variables showed linear variation when there was a difference on a continuous scale in the average of the healthy and dialysis groups, or average value variation when there was a difference on a nominal scale. Therefore, the same models were found in healthy persons and dialysis patients. Model 1 was analyzed using multiple regression analysis containing a qualitative scale, and model 2 was analyzed using multiple regression analysis. Looking at changes in each model caused by the arteriosclerosis factors, as arteriosclerosis progressed, the number of healthy persons increased and dialysis patients decreased. These results suggest that SPP increased in the early stages of arteriosclerosis and decreased in the later stages.

収録刊行物

• 日本透析医学会雑誌

  日本透析医学会雑誌 45 (12), 1141-1146, 2012

  一般社団法人 日本透析医学会

キーワード

• 血液透析
• 動脈硬化
• 数学モデル
• 皮膚灌流圧

詳細情報

• CRID: 1390001204678421760
• NII論文ID: 10031146692
• NII書誌ID: AN10432053
• DOI: 10.4009/jsdt.45.1141
• ISSN: 1883082X
• ISSN: 13403451
• NDL書誌ID: 024186372
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I024186372
• Web Site: https://search.jamas.or.jp/link/ui/2013148956
• 本文言語コード: ja
• データソース種別:
  • JaLC
  • NDL
  • Crossref
  • CiNii Articles
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