Casein phosphopeptide-amorphous calcium phosphate and glass ionomer show distinct effects in the remineralization of proximal artificial caries lesion in situ

DOI Web Site PubMed 被引用文献1件 参考文献58件
  • THEPYOU Rathapong
    Faculty of Dentistry, Chulalongkorn University
  • CHANMITKUL Wanvipa
    Faculty of Dentistry, Chulalongkorn University
  • THANATVARAKORN Ornnicha
    Cariology and Operative Dentistry, Department of Oral Health Sciences, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University
  • HAMBA Hidenori
    Cariology and Operative Dentistry, Department of Oral Health Sciences, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University
  • CHOB-ISARA Wanwalai
    Faculty of Dentistry, Chulalongkorn University
  • TRAIRATVORAKUL Chutima
    Department of Pediatric Dentistry, Faculty of Dentistry, Chulalongkorn University
  • TAGAMI Junji
    Cariology and Operative Dentistry, Department of Oral Health Sciences, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University Global Center Excellence (GCOE) Program, International Research Center for Molecular Science in Tooth and Bone Diseases, Tokyo Medical and Dental University

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  • Casein phosphopeptide-amorphous calcium phosphate and glass ionomer show distinct effects in the remineralization of proximal artificial caries lesion <i>in situ </i>

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This study aimed to compare the ability of casein-phosphopeptide amorphous-calcium-phosphate (CPP-ACP) and glass-ionomer (GI) in remineralizing proximal artificial caries lesions (ACLs). Molar enamel-slabs were divided into: original-lesion control, intra-oral controls, and experimental (CPP-ACP or GI) groups. Specimens received ACLs and were bonded on subject maxillary first molars. After 4-weeks, mineral density (MD) was analyzed by μCT. Compared to control, CPP-ACP increased MD at 0–38/68–84 microns and the GI group had an increase at 0–68 microns, with a greater increase in MD compared to the CPP-ACP group from 0–53 microns. The mean percent remineralization (%R) showed differences between the GI, CPP-ACP groups and their paired controls. GI tended to increase remineralization more than CPP-ACP. In conclusion, CPP-ACP and GI demonstrated distinct remineralizing ability. GI induced greater remineralization in the superficial lesion, while CPP-ACP remineralized the lesion body. Their effects on percent remineralization and reducing lesion depth of proximal ACLs were similar.

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