Changes in NAD Content Induced by Nicotinic Acid-Related Compounds in K562 Cells during Differentiation

• IDA Chieri

  Department of Bioscience, Nagahama Institute of Bio-Science and Technology

• OGATA Shin

  Laboratory of Molecular and Cellular Biology, Graduate School of Bioresources, Mie University

抄録

Two nicotinic acid-related compounds were found to induce erythroid differentiation in K562 cells. We investigated the changes in nicotinamide adenine dinucleotide (NAD) content induced by nicotinic acid-related compounds during differentiation. The NAD content was reduced by a treatment with nicotinic acid and isonicotinic acid. These results provide important clues toward elucidating the erythroid differentiation mechanism.

収録刊行物

• Ｂｉｏｓｃｉｅｎｃｅ，　Ｂｉｏｔｅｃｈｎｏｌｏｇｙ，　ａｎｄ　Ｂｉｏｃｈｅｍｉｓｔｒｙ

  Ｂｉｏｓｃｉｅｎｃｅ，　Ｂｉｏｔｅｃｈｎｏｌｏｇｙ，　ａｎｄ　Ｂｉｏｃｈｅｍｉｓｔｒｙ 77 (7), 1583-1585, 2013

  公益社団法人 日本農芸化学会

キーワード

• nicotinamide adenine dinucleotide (NAD)
• nicotinic acid
• isonicotinic acid
• cell differentiation
• K562

詳細情報

• CRID: 1390001206478876672
• NII論文ID: 10031190474
• NII書誌ID: AA10824164
• DOI: 10.1271/bbb.130131
• COI: 1:STN:280:DC%2BC3sjos1ejsg%3D%3D
• ISSN: 13476947
• ISSN: 09168451
• NDL書誌ID: 024723822
• PubMed: 23832340
• Web Site: http://id.ndl.go.jp/bib/024723822
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I024723822
• Web Site: http://www.tandfonline.com/doi/pdf/10.1271/bbb.130131
• Web Site: https://search.jamas.or.jp/link/ui/2014095546
• 本文言語コード: en
• データソース種別:
  • JaLC
  • NDL
  • Crossref
  • PubMed
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可