Examination of the carotid artery flow-velocity waveform velocity in hemodialysis patients

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  • 血液透析患者における頸動脈血流速度波形の検討
  • 血液透析患者における頸動脈血流速度波形の検討 : 頸動脈拡張末期最低血流速度の低値は脳・心血管障害の発症と関連する
  • ケツエキ トウセキ カンジャ ニ オケル ケイドウミャク ケツ リュウソクド ハケイ ノ ケントウ : ケイドウミャク カクチョウ マッキ サイテイ ケツ リュウソクド ノ テイチ ワ ノウ ・ シンケツカン ショウガイ ノ ハッショウ ト カンレン スル
  • : Low end diastolic velocity is related to the development of cerebro- and cardiovascular disorders
  • ―頸動脈拡張末期最低血流速度の低値は脳・心血管障害の発症と関連する―

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Abstract

Arteriosclerotic disease is a common complication in hemodialysis patients. We searched for a useful predictive factor for the presence of cerebro- and cardiovascular disorder (CCVD) based on hemodialysis patients' carotid artery flow-velocity waveforms. In 87 hemodialysis patients, the peak systolic velocity (PSV), end diastolic velocity (EDV), pulsatility index (PI) and end diastolic velocity ratio (ED ratio) were analyzed by carotid ultrasound examination. We examined the relationship between these flow-velocity waveforms and the maximum intima-media thickness (max-IMT), cardio-ankle vascular index (CAVI) and aortic calcification index (ACI). There were significant negative correlations between the EDV and max-IMT, CAVI and ACI. The EDV and ED ratio of the CCVD (+) group were significantly higher than those of the CCVD (-) group. We then divided all subjects into two groups according to the mean value of EDV (11 cm/sec). The incidence of CCVD in the lower-EDV group (<11 cm/sec) was significantly higher than that in the higher-EDV group (≥11 cm/sec). These findings suggest that the EDV and ED ratio are useful markers, as well as predictors of occlusive disease in hemodialysis patients. They further suggest that a low level of EDV is related to the incidence of CCVD in hemodialysis patients.

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