Cell proliferation and expression of Cbfa-1 in a peripheral osteo-chondroma arising from the mandibular oral mucosa of an edentulous alveolar ridge.
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- MATSUZAKA KENICHI
- Department of Clinical Pathophysiology, Oral Health Science Center, Tokyo Dental College
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- HAYASHI SEIICHI
- Hayashi Dental Clinic
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- SASAGURI KENICHI
- Department of Orthodontics, Kanagawa Dental College
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- SATO SADAO
- Department of Orthodontics, Kanagawa Dental College
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- TAKEMOTO KYOTO
- Department of Pathology, Oral Health Science Center, Tokyo Dental College
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- SHIMONO MASAKI
- Department of Pathology, Oral Health Science Center, Tokyo Dental College
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- INOUE TAKASHI
- Department of Clinical Pathophysiology, Oral Health Science Center, Tokyo Dental College
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抄録
This report describes the proliferation and the expression of Cbfa-1 in a rare case of peripheral osteo-chondroma arising from the mandibular oral mucosa of an edentulous alveolar ridge. Histologically, the lesion consisted of mesenchymal cells with either bone or cartilage tissue in the center. Almost all the tumor cells were reactive for PCNA, however, only the cells around the bone and cartilage tissues were reactive for Cbfa-1. These results suggest that both the bone and the cartilage tissues in this case were produced by mesenchymal cells that originated from the peripheral periosteum of the alveolar ridge. Furthermore, we have shown that immunohistochemical staining for PCNA and Cbfa-1 can be used to investigate lesions with bone or cartilage formation and to distinguish between those produced by osteogenic cells from those that are just reactive and produced by dystrophic calcification.
収録刊行物
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- The Bulletin of Tokyo Dental College
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The Bulletin of Tokyo Dental College 43 (3), 181-185, 2002
東京歯科大学
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詳細情報 詳細情報について
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- CRID
- 1390001204587542656
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- NII論文ID
- 110000008616
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- NII書誌ID
- AA00592969
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- COI
- 1:STN:280:DC%2BD38npsVCrtw%3D%3D
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- ISSN
- 00408891
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- PubMed
- 12455237
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- Crossref
- PubMed
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可