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The adsorption isotherms of acid dyes onto water-soluble and insoluble polymers containing cyclodextrin were measured in aqueous solution at 25℃. The acid dyes used were 10 azo dyes with different structures. The adsorption affinities of dyes with water-soluble polymer increased with increases in the length of alkly chain units in the dyes. The adsorption affinities of dyes with water-insoluble polymer increased with increases in the ratio of hydrophobic components in the dyes. The relationship between adsorption affinities and OSQR properties were also discussed in order to determine preferred adsorption behaviors of different cyclodextrin polymers and acid dyes.