Optimization of the Dengue-2 Antigen ELISA Titer for the Positive Case Detection of Dengue Virus Infection by IgM ELISA

IR
  • Aye Khin-Mar
    Department of Virology, Institute of Tropical Medicine, Nagasaki University
  • Thant Kyaw-Zin
    Department of Virology, Institute of Tropical Medicine, Nagasaki University
  • Thein Soe
    Virology Research Division, Department of Medical Research, Ministry of Health

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  • Institute of Tropical Medicine, Nagasaki University

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Abstract

We have determined the dengue-2 antigen ELISA titer for the positive case detection of dengue virus infection by IgM ELISA using 33 paired serum samples of dengue patients admitted to the North Okkalapa General Hospital, Yangon, Union of Myanmar, in June and July, 1994. The antigen ELISA titer was found to be over 32 units in order to find out sufficient number of positive cases. This finding can be used as a reference for further experiments and the development of tetravalent dengue antigen for routine serodiagnosis of dengue virus infection.

Journal

  • Tropical medicine

    Tropical medicine 37 (3), 123-128, 1995-12-26

    Nagasaki University

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