ML-236B (Compactin) as an Inhibitor of Juvenile Hormone Biosynthesis

• HIRUMA K.

  Department of Medical Entomology, National Institute of Health

• YAGI Shigemi

  Laboratory of Applied Entomology and Laboratory of Microbiology and Fermentation, Faculty of Agriculture, Tokyo University of Agriculture and Technology

• ENDO Akira

  Laboratory of Applied Entomology and Laboratory of Microbiology and Fermentation, Faculty of Agriculture, Tokyo University of Agriculture and Technology

抄録

ML-236B (Compactin), an inhibitor of HMG-CoA reductase activity and thus of juvenile hormone (JH) biosynthesis, was found to have anti-JH action in the cabbage armyworm, Mamestra brassicae. When 50 μg ML-236B was injected twice or three times every 6 or 9 hr respectively beginning 18 hr before head capsule slippage in the penultimate instar, it caused the formation of larval-pupal intermediates. Later application 6 hr after head capsule slippage only inhibited ommochrome synthesis. This latter effect could be prevented by simultaneous application of JH-I. Thus, ML-236B apparently prevents JH biosynthesis for a short period, but is rapidly metabolized so that the effect is reversible.

収録刊行物

• Appl. Ent. Zool.

  Appl. Ent. Zool. 18 111-115, 1983

  日本応用動物昆虫学会

詳細情報

• CRID: 1571980076820424192
• NII論文ID: 110001105651
• NII書誌ID: AA00543238
• ISSN: 00036862
• 本文言語コード: en
• データソース種別:
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