術後２９年目に肺・胸膜転移をきたした乳癌の１例―胸水細胞所見を中心に―

DOI 被引用文献1件 参考文献12件
  • 橋本 潔
    鳥取大学医学部基盤病態医学講座器官病理学
  • 荒木 邦夫
    鳥取大学医学部基盤病態医学講座器官病理学
  • 庄盛 浩平
    鳥取大学医学部基盤病態医学講座器官病理学
  • 宮田 昌典
    鳥取大学医学部統合内科医学講座分子制御内科学
  • 安田 和人
    鳥取大学医学部統合内科医学講座分子制御内科学
  • 重岡 靖
    鳥取大学医学部統合内科医学講座分子制御内科学
  • 清水 英治
    鳥取大学医学部統合内科医学講座分子制御内科学
  • 井藤 久雄
    鳥取大学医学部基盤病態医学講座器官病理学

書誌事項

タイトル別名
  • A case of postoperative lung and pleural metastasis after 29 years in a breast cancer patient-Cytological findings of the pleural effusion-
  • Cytological findings of the pleural effusion
  • 胸水細胞所見を中心に

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Background: Breast cancer tends to recur more often after long-term latency than other malignancies. Most recurrence, however, is within 5 years after curative surgery and rare or never after 15 years. A favorable prognosis may be expected in patients with estrogen-receptor-positive breast cancer. We report a case with recurrence and metastases of breast cancer diagnosed 29 years after curative surgery. Case: A 74-year-old woman underwent radical mastectomy followed by radiation and chemotherapy for ductal carcinoma of the breast 29 years earlier. When she consulted a doctor for dyspnea on effort, she was found in computed tomography of the chest to have right pleural effusion and atelectasis of the right middle lobe of the lung. Cytology of the pleural effusion showed numerous cancer cell clusters that showed positive immunoreactivity for estrogen receptor, progesterone receptor, and c-erbB-2 in paraffin-embedded cell block specimens. No abnormal lesion was noted in the uterus. These findings led us to diagnose the cancer as recurrent breast cancer. Conclusion: This case shows that breast cancer may recur, more than 15 years after curative surgery.

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