コンセンサスシンポジウム　　子宮内膜機能性出血の細胞診　　内膜細胞診疑陽性例の再検討から

DOI 被引用文献8件 参考文献14件

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  • Consensus symposium. Endometrial cytology of dysfunctional uterine bleeding. Retrospective study on suspicious cases.
  • Retrospective study on suspicious cases
  • 内膜細胞診疑陽性例の再検討から

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Objective: Most cases in which endometrial cytology is suspicious show no organic disease, although endometrial carcinoma and hyperplasia may be detected. We reanalyzed the cytology of dysfunctional bleeding, whose main representatives were of nonorganic disease.<BR>Study design: Subjects were 365 cases of suspicious endometrial cytology including 104 with dysfunctional bleeding. Of these, 87 with no organic diseases underwent endometrial biopsy within 1 year. Endometrial cytology slides were rescreened and reevaluated based on our criteria (12 parameters) in diagnosing complex endometrial hyperplasia.<BR>Results: (1) Of 365 cases with suspicious cytology, 221 (60.5%), had no organic abnormality, and 104 (47.0% of nonorganic cases, 37.0% of all suspicious cases) were diagnosed as dysfunctional uterine bleeding.(2) After rescreening, 74.4% of 87 cases (negative group) were evaluated as negative and 25.3%(suspicious group) remained suspicious.(3) Concerning 12 parameters for complex endometrial hyperplasia, 22.7% cases in the suspicious group had more than 8 parameters, whereas all cases in the negative group had less than 4 parameters.(4) In the negative group, causes for initially suspicious cytology were due to cyclic changes in the endometrium (37.0%), abnormal hormonal status (39.9%), and metaplasia/tissue repair and infection (23.1%).<BR>Conclusion: Dysfunctional uterine bleeding accounted for 37.0% of all suspicious cases in endometrial cytology, 74.7% of suspicious dysfunctional bleeding cases can be ruled out when specimens were strictly evaluated based on hormonal status, metaplasia/tissue repair, and complex hyperplasia criteria.

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