Study on Hepatocellular Carcinomas with Extrahepatic Malignancies.

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  • 肝細胞癌と他臓器癌との重複癌症例

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Abstract

In 108 patients with hepatocellular carcinoma (HCC), 8 (7.4%) had extrahepatic malignancies. Seven had synchronous multiple primary malignancies and one had a metachronous cancer. Gastric cancer was the most common malignancy combined with HCC. It was considered that the upper gastrointestinal series was necessary for the patient with HCC. The frequency of liver cirrhosis was 62.5% in the patients with multiple primary cancers (n=8) and 91% in those with non-multiple primary cancers (n=100) (p<0.05). Retention rate of indocyanine green was 13.9±6.6% and 22.9±13.0% respectively (p<0.05). The frequency of positive HBsAg was 0% and 29% respectively. It was suggested that factors different from those of the ordinary HCC participate in multiple primary cancers.

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