胆管内乳頭状発育を呈した早期肝内胆管癌の１例

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  • A Case of Early Intrahepatic Cholangiocarcinoma with Intraductal Papillary Growth.

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A 66-year-old man presented with early intrahepatic cholangiocarcinoma with intraductal papillary growth. Abdominal US showed a high echogenic mass in the left hepatic duct. The left lobe, the caudate lobe and the left hepatic duct were resected. The tumor showed expansive growth in the left hepatic duct without invasion to the parenchyma of the liver. Histologically, the tumor showed various structual atypia with little mucin production, and was limited to the mucosa. Immunohistologically, intestinal-type apomucin was expressed in this tumor, but mammary-type was not. We diagnosed this tumor as an early intraductal papillary cholangiocarcinoma. The patient is doing well without the evidence of recurrence 50 months after surgery. Seven cases of intraductal cholangiocarcinoma including our case have been reported in the Japanese literatures. All the tumors except ours have been reported as mucin-producing cholangiocarcinomas. Patients with intraductal papillary cholangiocarcinoma which is limited to the mucosa of fibromuscular layer could be given a good prognosis by surgery.

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