術中迅速細胞診で診断した網膜芽細胞腫

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  • Cytology of undifferentiated retino blastoma.

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We studied a case of undifferentiated retinoblastoma in which fine needle biosy established the correct diagnosis. This 3-year-old girl was referred because of cloudy vitreous body. Examination of the left eye disclosed retrolental mass. Ultrasound and computed tomography demonstrated the mass without detectable calcification. The smears of the aspiration were richly cellular and showed a few intact retinoblastoma cells. The cells occurred in loose clusters or individually and had scanty cytoplasms and round hyperchromatic nuclei. In the background are abundant ghost cells without inflammatory cells. Immunohistochemically, most tumor cells reacted with NSE: a few cells reacted with GFAP.

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