SEM studies of Microangiopathy in the Streptozotocin-Induced Diabetic Rat

  • YASUOKA Ryosuke
    First Department of Oral and Maxillofacial Surgery, Osaka Dental University

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Other Title
  • 糖尿病ラットにおける細小血管症について

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Abstract

Microvascular changes during microangiopathy in the diabetic rat retina and gingivae, especially the inner marginal epithelium of the gingiva, were investigated under TEM utilizing microvascular casts prepared by the plastic injection method. The endothelium of the retinal capillaries was also investigated under TEM.<br> The progress of microangiopathy in the retinal capillaries was examined 10 weeks after injection of streptozotocin. Microangiopathy in the inner marginal epithelium closed up rapidly 20 weeks after streptozotocin injection. This was accomapanied by microvasculature changes.<br> Investigation of the retinal vascular architecture due to microangiopathy was helpful in determining the severity of the diabetic condition.

Journal

  • Shikaigaku

    Shikaigaku 53 (4), 361-373, 1990

    Osaka Odontological Society

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