Bleomycin局所療法用製剤の研究

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書誌事項

タイトル別名
  • Local Cancer Therapy with Bleomycin Mixed in Aluminum Soap Solution

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抄録

Local therapy of postoperative cancers with bleomycin was studied. Bleomycin was mixed in various bases, and inserted into the local site with a hemostatic gelatin sponge. In the in vitro and in vivo tests, bleomycin in aluminum soap solution (compound of aluminum monostearate and sesame oil) as a base proved most excellent from the viewpointof local retention, tissue permeability and local hemostatic effect. The preparation produced no undesirable effects on the normal tissue. The therapeutic effect was sustained long. It is, therefore, considered that aluminum soap solution is the base of first choice in the local bleomycin therapy.

収録刊行物

  • 病院薬学

    病院薬学 1 (4), 230-233, 1976

    一般社団法人 日本医療薬学会

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