Pharmaceutical Studies on Commercial Cephalexin Capsules
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- ASADA TAKESHI
- Osaka Kosei Nenkin Hospital Pharmacy
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- OHORI MASATO
- Osaka Kosei Nenkin Hospital Pharmacy
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- KAMON TAKASHI
- Osaka Kosei Nenkin Hospital Pharmacy
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- NAKAGAWA HARUO
- Osaka Kosei Nenkin Hospital Pharmacy
Bibliographic Information
- Other Title
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- セファレキシンカプセルの薬剤学的検討
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Abstract
Commercial cephalexin capsules were compared in terms of their in vivo absorption in humans, as well as of weight variations, disintegration and dissolution rates. No significant difference was found in dissolution rates among five of the six brands examined, but in the remaining one brands maximum plasma concentration was lower and the time for the concentration to reach the maximum level was varied between capsulles. That may be attributed to slow dispersion of the granule taken out from the capsules. Bioavailability of cephalexin, a readily absorbable substance, may largely depend on lubricants or granulation methods.
Journal
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- Japanese Journal of Hospital Pharmacy
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Japanese Journal of Hospital Pharmacy 3 (1), 25-29, 1977
Japanese Society of Pharmaceutical Health Care and Sciences
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Details 詳細情報について
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- CRID
- 1390282679752319104
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- NII Article ID
- 110001796655
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- NII Book ID
- AN00002794
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- ISSN
- 21859477
- 03899098
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- Data Source
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- JaLC
- Crossref
- NDL-Digital
- CiNii Articles
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- Abstract License Flag
- Disallowed